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eIF-3E (EIF3E),Rabbit Monoclonal Antibod

eIF-3E (EIF3E),Rabbit Monoclonal Antibod

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价格:¥电议

更新日期:2026/8/25 1:09:24

生 产 地:中国大陆

产品型号:

简单介绍:eIF-3E (EIF3E),Rabbit Monoclonal Antibod
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6877
【用途】WB , ICC
【抗原分子量】48kDa

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相关标签:eIF-3E,(EIF3E),Rabbit,Monoclonal,Antibod

详细内容

eIF-3E (EIF3E)
Rabbit Monoclonal Antibody
Cas 号:
分子式:
别 名: EIF3E antibody, EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, Eukaryotic translation initiation factor 3 subunit E antibody, Eukaryotic translation initiation factor 3 subunit 6 antibody, Viral integration site protein INT-6 homolo
订货信息:
货号 品名 规格 包装 单价 货期 订购
eIF-3E (EIF3E) 100ul 询价 现货 订购
性 状:

【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6877
eIF-3E (EIF3E),Rabbit Monoclonal Antibod

【用途】WB , ICC
【抗原分子量】48kDa

质量标准: 【产品介绍】eIF-3E is the p48 subunit of the
translational initiation factor eIF3. It forms a
multi-factor complex with eIF1, eIF5, and the
eIF2-GTP-Met-tRNA ternary complex that binds to the
40S ribosomal subunit to form the 43S preinitiation
complex (PIC). eIF-3E also prevents the premature joining
of the 60S ribosomal subunit until the start codon
is recognized. In addition, eIF-3E plays a role
in recruiting eIF4G-associated mRNAs to the 43S PIC to
form the 48S PIC and initiate mRNA scanning (1). It
is required for nonsense-mediated mRNA decay (NMD) and
acts in conjunction with UPF2 to divert mRNAs
from translation to the NMD pathway. eIF-3E also
interacts with MCM7 and EPAS1 and regulate the
proteasome-mediated degradation of these proteins (2).

eIF-3E (EIF3E),Rabbit Monoclonal Antibod
Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
Species Reactivity *

eIF-3E (EIF3E),Rabbit Monoclonal Antibod

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

eIF-3E (EIF3E),Rabbit Monoclonal Antibod

Western blot analysis on (A) Jurkat, (B) 293T,
(C) BxPC-3, (D) A431, (E) Saos-2, (F) HepG2, and (G)
NIH/3T3 cell lysates using anti-eIF-3E RabMAb (cat. #5387-1).

Specificity

A synthetic peptide corresponding to residues in
human eIF-3E was used as an immunogen.

贮 存: Storage Condition and Buffer

eIF-3E (EIF3E),Rabbit Monoclonal Antibod

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

eIF-3E,(EIF3E),Rabbit,Monoclonal,Antibod

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