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DLC8 (N-term),Rabbit Monoclonal IgG

DLC8 (N-term),Rabbit Monoclonal IgG

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价格:¥电议

更新日期:2026/8/25 1:09:24

生 产 地:中国大陆

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简单介绍:DLC8 (N-term),Rabbit Monoclonal IgG
【反应特异性】Human , Mouse , Rat
【克隆 ID】EP1660Y
【用途】WB , IHC , ICC , IP
【抗原分子量】10 kDa

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相关标签:DLC8,(N-term),Rabbit,Monoclonal,IgG

详细内容

DLC8 (N-term)
Rabbit Monoclonal IgG
Cas 号:
分子式:
别 名: Dynein light chain LC8-type 1, 8 kDa dynein light chain, DLC8, Protein inhibit o r of neuronal nitric oxide synthase, PIN
订货信息:
货号 品名 规格 包装 单价 货期 订购
DLC8 (N-term) 100ul 询价 现货 订购
性 状:

【反应特异性】Human , Mouse , Rat
DLC8 (N-term),Rabbit Monoclonal IgG

【克隆 ID】EP1660Y
【用途】WB , IHC , ICC , IP
【抗原分子量】10 kDa

质量标准: 【产品介绍】DLC8 protein bound efficiently to gephyrin in
in vitro binding assays a n d colocalized with
gephyrin during coexpression in HEK293 cells. The
binding site f o r DLC8 was mapped to a fragment of 63
amino acids within the central linker domain of gephyrin.
In hippocampal neurons, endogenous DLC8 protein was
enriched at synaptic sites identified by synaptophysin
a n d gephyrin immunostaining. Because DLC8 has
been described as stoichiometric components of
cytoplasmic dynein a n d myosin-Va complexes,
results suggest that mot o r proteins are involved in
the subcellular localization of gephyrin (1). DLC8
was identified as a transp o r t molecule in the
cytoplasm. DLC8 co-localizes with TRPS1 in
dot-like structures in the cell nucleus. In an electroph
o r etic mobility shift assay it was shown that
the interaction of DLC8 a n d TRPS1 lowers the binding
of TRPS1 to the GATA consensus sequence. In addition DLC8
is able to suppress the transcriptional repression
activity of TRPS1 (2).

DLC8 (N-term),Rabbit Monoclonal IgG
WB: 1:10,000
IHC: 1:100 250
ICC: 1:100 250
IP: 1:100

A. Western blot analysis on HeLa cell lysate using
anti-DLC8 RabMAb (cat. # 2003-1), dilution 1:10,000.

DLC8 (N-term),Rabbit Monoclonal IgG

B. Immunohistochemical staining of paraffin-embedded
human liver using anti-DLC8 RabMAb (cat. #2003-1).

DLC8,(N-term),Rabbit,Monoclonal,IgG

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