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Cytokeratin 8,Rabbit Monoclonal IgG

Cytokeratin 8,Rabbit Monoclonal IgG

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价格:¥电议

更新日期:2026/8/25 1:09:24

生 产 地:中国大陆

产品型号:

简单介绍:Cytokeratin 8,Rabbit Monoclonal IgG
【反应特异性】Human
【克隆 ID】EP1628Y
【用途】WB , IHC , ICC , FC , IP
【抗原分子量】52 kDa

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相关标签:Cytokeratin,8,Rabbit,Monoclonal,IgG

详细内容

Cytokeratin 8
Rabbit Monoclonal IgG
Cas 号:
分子式:
别 名: Cytokeratin-8, CK-8, Keratin-8, K8
订货信息:
货号 品名 规格 包装 单价 货期 订购
Cytokeratin 8 100ul 询价 现货 订购
性 状:

【反应特异性】Human
【克隆 ID】EP1628Y
Cytokeratin 8,Rabbit Monoclonal IgG

【用途】WB , IHC , ICC , FC , IP
【抗原分子量】52 kDa

质量标准: 【产品介绍】Keratins, the intermediate filament proteins
of epithelial cells, connect to desmosomes, the
cell-cell adhesion structures at the surface membrane.
Among the various intermediate filament (IF)
proteins, cytokeratin 8 (CK8) is especially remarkable as
it is produced early in embryogenesis, is the only
type-II CK occurring in many simple epithelial cells,
a n d can also be synthesized in certain
non-epithelial cells (1). Keratin 8 a n d 18 (CK8/18)
are the maj o r keratin pair in simple-type epithelia,
as found in the liver, pancreas, a n d intestine (2).
While K8/K18 are essential f o r maintaining
structural integrity, there is accumulating
evidence indicating that they also exert
non-mechanical functions. It has been rep o r ted
that K8/K18-free hepatocytes from K8-null mice are
m o r e sensitive to Fas-mediated apoptosis, in line with
an increased Fas density at the cell surface a n d
an altered c-Flip regulation of the anti-apoptotic
ERK1/2 signaling pathway (3).

Cytokeratin 8,Rabbit Monoclonal IgG
WB: 1:25,000 50,000
IHC: 1:250 500
ICC: 1:100 250
Flow Cytometry: 1:20
IP: 1:70

Cytokeratin 8,Rabbit Monoclonal IgG

A. Western blot analysis on A431 cell lysate using
anti-CK8 RabMAb(cat. # 2032-1), dilution 1:50,000.

B. Immunohistochemical analysis of paraffin-embedded
human breast adenocarcinoma using anti-CK8
RabMAb (cat. #2032-1).

Cytokeratin,8,Rabbit,Monoclonal,IgG

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