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Cyclin E1 Phospho (pT77) (CCNE1),Rabbit

Cyclin E1 Phospho (pT77) (CCNE1),Rabbit

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价格:¥电议

更新日期:2026/8/25 1:09:24

生 产 地:中国大陆

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简单介绍:Cyclin E1 Phospho (pT77) (CCNE1),Rabbit
【反应特异性】Human
【克隆 ID】EPR2242(2)
【用途】WB , IHC , ICC
【抗原分子量】50kDa

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相关标签:Cyclin,E1,Phospho,(pT77),(CCNE1),Rabbit

详细内容

Cyclin E1 Phospho (pT77) (CCNE1)
Rabbit Monoclonal Antibody
Cas 号:
分子式:
别 名: CCNE1 antibody, CCNE antibody, G1/S-specific cyclin-E1 antibody, antibody
订货信息:
货号 品名 规格 包装 单价 货期 订购
Cyclin E1 Phospho (pT77) (CCNE1) 100ul 询价 现货 订购
性 状:

【反应特异性】Human
【克隆 ID】EPR2242(2)
Cyclin E1 Phospho (pT77) (CCNE1),Rabbit

【用途】WB , IHC , ICC
【抗原分子量】50kDa

质量标准: 【产品介绍】Cyclin E1 is a member of the cyclin E
family that can associate with and activate
cyclin-dependent kinase Cdk2. Expression of cyclin E1
is essential for the control of the cell cycle at the
late G1 and early S phase (1). The cyclin E/Cdk2
complex plays an essential and limiting role in
the transition between G1 and S phase as well as
the initiation of DNA replication (2) Ubiquination by
the Cul-3 pathway and by Fbw7 regulates cyclin E1 levels
and is critically important in normal cells. Abnormally
high levels of cyclin E expression have frequently
been observed in human cancers (3). Moreover, high cyclin
E1 levels correlate with increased tumor aggression and
poor prognosis (4).

Cyclin E1 Phospho (pT77) (CCNE1),Rabbit
Recommended Applications

WB, IHC, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:250 - 500
Species Reactivity *

Cyclin E1 Phospho (pT77) (CCNE1),Rabbit

Human

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on JAR cell lysates using
anti-Phospho-Cyclin E1 (pT77) RabMAb (cat. #5105-1).
Cells were either (A) untreated or (B) treated with
Lambda Phosphatase.

Cyclin E1 Phospho (pT77) (CCNE1),Rabbit

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-Phospho-Cyclin E1
(pT77) RabMAb (cat. #5105-1).

Specificity

Cyclin E1 Phospho (pT77) (CCNE1),Rabbit

A phospho specific peptide corresponding to
residues surrounding Threonine 77 of human Cyclin E1
was used as an immunogen. This antibody only detects
Cyclin E1 phosphorylated at Threonine 77.

贮 存: Storage Condition and Buffer

Cyclin E1 Phospho (pT77) (CCNE1),Rabbit

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

Cyclin,E1,Phospho,(pT77),(CCNE1),Rabbit

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