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CD209,Rabbit Monoclonal Antibody

CD209,Rabbit Monoclonal Antibody

点击次数:211

价格:¥电议

更新日期:2026/8/25 1:09:24

生 产 地:中国大陆

产品型号:

简单介绍:CD209,Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR5588
【用途】WB , IHC
【抗原分子量】50kDa

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相关标签:CD209,Rabbit,Monoclonal,Antibody

详细内容

CD209
Rabbit Monoclonal Antibody
Cas 号:
分子式:
别 名: CD209 antibody, CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, MGC129965 antibody, CD209 antigen antibody, C-type lectin domain family 4 member L antibody, Dendritic cell-specific ICAM-3-grabbing non-integrin 1 antibody
订货信息:
货号 品名 规格 包装 单价 货期 订购
CD209 100ul 询价 现货 订购
性 状:

【反应特异性】Human
【克隆 ID】EPR5588
CD209,Rabbit Monoclonal Antibody

【用途】WB , IHC
【抗原分子量】50kDa

质量标准: 【产品介绍】CD209 is a transmembrane receptor and is
often referred to as DC-SIGN because of its expression
on the surface of dendritic cells and macrophages. It
is involved in the innate immune system and
recognizes numerous evolutionarily divergent
pathogens, ranging from parasites to viruses with a
large impact on public health. CD209 is organized into
three distinct domains: an N-terminal transmembrane
domain, a tandem-repeat neck domain and C-type
lectin carbohydrate recognition domain. The
extracellular region consisting of the C-type lectin
and neck domains has a dual function as a
pathogen recognition receptor and a cell adhesion
receptor by binding carbohydrate ligands on the surface
of microbes and endogenous cells. The neck region
is important for homo-oligomerization which allows
the receptor to bind multivalent ligands with high
avidity. Variations in the number of 23 amino acid
repeats in the neck domain of this protein are rare but
have a significant impact on ligand binding ability.
CD209 is closely related in terms of both sequence
and function to a neighboring protein L-SIGN. DC-SIGN
and L-SIGN differ in their ligand-binding properties
and distribution (1).

CD209,Rabbit Monoclonal Antibody
Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:50 - 100
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

CD209,Rabbit Monoclonal Antibody
Products Data

Western blot analysis on (A) HACAT, (B) fetal skin,
(C) fetal artery, and (D) human small intestine
lysates using anti-CD209 RabMAb (cat. #5232-1).

CD209,Rabbit Monoclonal Antibody
Immunohistochemical analysis of paraffin-embedded
human placenta tissue using anti-CD209 RabMAb (cat.# 5232-1).

Specificity

A synthetic peptide corresponding to residues in human
CD209 was used as an immunogen.

贮 存: Storage Condition and Buffer

CD209,Rabbit Monoclonal Antibody

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

CD209,Rabbit,Monoclonal,Antibody

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