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Anti-5 lipoxygenase/ALOX55-脂氧合酶抗体

Anti-5 lipoxygenase/ALOX55-脂氧合酶抗体

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价格:¥电议

更新日期:2026/9/8 4:13:22

生 产 地:其它

产品型号:BY-0526R

简单介绍:本公司经销5 lipoxygenase/ALOX5,5-脂氧合酶抗体,克隆类型为polyclonal,宿主来源是Rabbit,5 lipoxygenase/ALOX55-脂氧合酶抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

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相关标签:5,lipoxygenase/ALOX5,5-脂氧合酶抗体,5,lipoxyge

详细内容

本公司经销5 lipoxygenase/ALOX5,5-脂氧合酶抗体,克隆类型为polyclonal,宿主来源是Rabbit,5 lipoxygenase/ALOX55-脂氧合酶抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

货号:BY-0526R
英文名称:Anti-5 lipoxygenase/ALOX5
中文名称:5-脂氧合酶抗体
其他名称:名5-lipoxygenase; 5-LOX; 5 LO; 5LPG; ALOX 5; ALOX5; Arachidonate 5 lipoxygenase; Arachidonic acid 5 lipoxygenase; Leukotriene A4 synthase; LOG 5; LOG5; MGC163204.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 78kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, hrs, pig, dog, Rb
产品介绍:This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans⁻⁷,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.Subunit : Interacts with ALOX5AP and LTC4S.Subcellular Location : Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. Similarity : Belongs to the lipoxygenase family.Contains 1 lipoxygenase domain.Contains 1 PLAT domain.合成与降解(Synthesis and Degradation) 5-脂氧合酶蛋白是花生四烯酸代谢途径中的一种关键酶,在恶性肿瘤的发生、发展过程中起了重要作用。抑制5-脂氧合酶及其产物的表达有可能预防和逆转恶性肿瘤的发生。产品图片Protein: line1, rat brain lysates, 30ug; line2, mouse intestine lysates, 30ug; Primary: Anti-5 lipoxygenase (bs-0526R) at 1:200; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000; ECL excitated the fluorescence; Predicted band size : 78kDObserved band size : 40kD, 78kDWe are unsure as to the identity of these extra bands
5,lipoxygenase/ALOX5,5-脂氧合酶抗体,5,lipoxyge

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