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"Anti-SRD5A1
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价格：￥电议
更新日期：2026/9/8 4:13:22
生 产 地：其它
产品型号：BY-11308R
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相关标签：",SRD5A1,
详细内容
"本公司经销SRD5A1，，克隆类型为polyclonal，宿主来源是Rabbit，SRD5A1可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！
货号：BY-11308R
英文名称：Anti-SRD5A1
中文名称：
其他名称：
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone, which mediates androgen effects on target tissues. The enzyme exists as two isoforms: type 1, which is expressed mainly in the skin; ａnd type 2, which is expressed mainly in the prostate. In cultured human skin cells, 5a-Reductase 1 shows heterogeneity of protein, ａnd has different levels of transcriptional ａnd translational expression. 5a-Reductase 1 is expressed in all portions of the hair follicle, whereas 5a-Reductase 2 is expressed only in mesenchymal portions. In addition, 5a-Reductase 1 is mainly expressed in human breast carcinoma ａnd may play a role in the in situ production ａnd actions of the potent androgen 5a-dihydrotestosterone, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma. The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids.Function : Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.Subcellular Location : Membrane.Tissue Specificity : Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea ａnd spinal cord. Lower levels found in skeletal muscle, intestine ａnd lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.Similarity : Belongs to the short-chain dehydrogenases/reductases （SDR） family."
货号：BY-11308R
英文名称：Anti-SRD5A1
中文名称：
其他名称：
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone, which mediates androgen effects on target tissues. The enzyme exists as two isoforms: type 1, which is expressed mainly in the skin; ａnd type 2, which is expressed mainly in the prostate. In cultured human skin cells, 5a-Reductase 1 shows heterogeneity of protein, ａnd has different levels of transcriptional ａnd translational expression. 5a-Reductase 1 is expressed in all portions of the hair follicle, whereas 5a-Reductase 2 is expressed only in mesenchymal portions. In addition, 5a-Reductase 1 is mainly expressed in human breast carcinoma ａnd may play a role in the in situ production ａnd actions of the potent androgen 5a-dihydrotestosterone, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma. The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids.Function : Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.Subcellular Location : Membrane.Tissue Specificity : Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea ａnd spinal cord. Lower levels found in skeletal muscle, intestine ａnd lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.Similarity : Belongs to the short-chain dehydrogenases/reductases （SDR） family."
",SRD5A1,
