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FLT4 Human/重组人血管内皮生长因子受体3
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FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
Synonyms Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. Introduction All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Description Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. Source Insect Cells. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. Solubility It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a）Analysis by RP-HPLC.
（b）Analysis by SDS-PAGE. Biological Activity Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FLT4 Human/重组人血管内皮生长因子受体3
产品编号：PKA-244
产品规格：2μg/10μg/1mg
产品规格：2μg/10μg/1mg
| Synonyms | Tyrosine-protein kinase receptor FLT4, PCL, FLT41, FMS-like TYROSINE KINASE 4, VEGFR-3, VEGFR3. |
| Introduction | All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases （RTKs） characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular ａnd lymphatic endothelial cells ａnd to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis ａnd lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid （aa） residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain ａnd a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C ａnd VEGF-D have been shown to bind ａnd activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. |
| Description | Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25⁻⁷74 amino acids ａnd having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques. |
| Source | Insect Cells. |
| Physical Appearance | Sterile Filtered White lyophilized （freeze-dried） powder. |
| Formulation | FLT4 was lyophilized from a concentrated （1 mg/ml） sterile solution containing 1x PBS. |
| Solubility | It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2⁻⁷ days ａnd for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Purity | Greater than 90.0% as determined by（a）Analysis by RP-HPLC. （b）Analysis by SDS-PAGE. |
| Biological Activity | Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 μg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
FLT4,Human,重组人血管内皮生长因子受体3
