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ARG1 Human/ 重组人肝脏精氨酸酶

ARG1 Human/ 重组人肝脏精氨酸酶

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简单介绍:ARG1 Human/ 重组人肝脏精氨酸酶

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ARG1 Human/ 重组人肝脏精氨酸酶

产品编号:ENZ-517
产品规格:5μg/25μg/1mg
Synonyms EC 3.5.3.1, Arginase 1, Type I Arginase, Liver-Type Arginase.
Introduction ARG1 catalyzes the hydrolysis of arginine to ornithine and urea. 2 isoforms of mammalian arginase exist which vary in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic role. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia.
Description ARG1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 330 amino acids (1-322a.a.) and having a molecular mass of 35.8 kDa. ARG1 protein is fused to a 8 amino acid His tag at C-terminus and is purified by standard chromatography.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation ARG1 Human solution containing 20mM Trsi HCL pH-8, 2mM DTT, 0.1M NaCl & 20% glycerol.
Stability ARG1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino acid sequence MSAKSRTIGI IGAPFSKGQP RGGVEEGPTV LRKAGLLEKL KEQECDVKDY GDLPFADIPN DSPFQIVKNP RSVGKASEQL AGKVAEVKKN GRISLVLGGD HSLAIGSISG HARVHPDLGV IWVDAHTDIN TPLTTTSGNL HGQPVSFLLK ELKGKIPDVP GFSWVTPCIS AKDIVYIGLR DVDPGEHYIL KTLGIKYFSM TEVDRLGIGK VMEETLSYLL GRKKRPIHLS FDVDGLDPSF TPATGTPVVG GLTYREGLYI TEEIYKTGLL SGLDIMEVNP SLGKTPEEVT RTVNTAVAIT LACFGLAREG NHKPIDYLNP PKLEHHHHHH.
Purity Greater than 85% as determined by SDS-PAGE.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ARG1,Human,重组人肝脏精氨酸酶

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