联系我们
联系人：陈先生
产品展示
Flap Structure-Specific Endonuclease 1 Human Recombinant
点击次数：394
价格：￥电议
更新日期：2026/8/24 23:18:11
生 产 地：欧洲
产品型号：
商家名片
陈**
联系我时，请说明是阿仪网看到的，谢谢!
- 电话: 05*******891
- 手机: 18******628
- 微信:
- 交换名片后展示联系方式 → →
相关标签：Flap,Structure-Specific,Endonuclease,1,H
详细内容
慧嘉生物您实验身边的好伙伴
为客户提供“最高品质的产品”和“最优质的服务”
AssayBiotech CUSABIO Immunoway Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec lifespan BD
欢迎广大客户咨询，另有大量宣传海报和小礼品赠送。
网站：www..com
Q Q：
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
Synonyms FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. Introduction FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. Description FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino acid sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Flap Structure-Specific Endonuclease 1 Human Recombinant
产品编号：ENZ-468
产品规格：5μg/20μg/1mg
产品规格：5μg/20μg/1mg
| Synonyms | FEN-1, MF1, RAD2, Maturation Factor-1, MF-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, DNase IV, FEN1. |
| Introduction | FEN1 removes 5＇＇ overhanging flaps in DNA repair ａnd processes the 5＇＇ ends of Okazaki fragments in lagging strand DNA synthesis. The interaction between FEN1 ａnd AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, therefore passing the substrate from one enzyme to another. FEN1 is part of the XPG/RAD2 endonuclease family ａnd is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5＇＇ end of the flap that is necessary for both binding ａnd cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. |
| Description | FEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids （1-380 a.a.） ａnd having a molecular mass of 42.5 kDa. The FEN1 protein is purified by standard chromatogrpahy techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile filtered colorless solution. |
| Formulation | The protein contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol ａnd 100mM NaCl. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Amino acid sequence | MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Flap,Structure-Specific,Endonuclease,1,H
