联系我们
联系人：陈先生
产品展示
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
点击次数：372
价格：￥电议
更新日期：2026/8/24 23:18:11
生 产 地：欧洲
产品型号：
商家名片
陈**
联系我时，请说明是阿仪网看到的，谢谢!
- 电话: 05*******891
- 手机: 18******628
- 微信:
- 交换名片后展示联系方式 → →
相关标签：HDAC1,Human,重组人组蛋白脱乙酰基酶1
详细内容
慧嘉生物您实验身边的好伙伴
为客户提供“最高品质的产品”和“最优质的服务”
AssayBiotech CUSABIO Immunoway Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec lifespan BD
欢迎广大客户咨询，另有大量宣传海报和小礼品赠送。
网站：www..com
Q Q：
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
HDAC1 Human/ 重组人组蛋白脱乙酰基酶1
产品编号：ENZ-424
产品规格：5μg/20μg/1mg
Synonyms HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. Introduction HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. Description HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa.
The HDAC1 is purified by proprietary chromatographic techniques. Source Hi-5 Baculovirus. Physical Appearance Sterile Filtered colorless solution. Formulation The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. Stability HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino acid sequence MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
产品规格：5μg/20μg/1mg
| Synonyms | HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, HDAC1, Histone deacetylase 1. |
| Introduction | HDAC1 is a member of the histone deacetylase/acuc/apha family ａnd a component of the histone deacetylase complex. HDAC1 is in charge of the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 ａnd H4）. Histone acetylation ａnd deacetylation, catalyzed by multi-subunit complexes, are a crucial factor in the regulation of eukaryotic gene expression. In addition, HDAC1 interacts with retinoblastoma tumor-suppressor protein ａnd this complex is a major factor in the control of cell proliferation ａnd differentiation. Low levels of HDAC1 were linked to breast cancer progression. Studies have shown that cancer cells successfully maintained decreased levels of pyruvate to prevent inhibition of HDAC1/HDAC3 ａnd thus to escape cell death. HDAC1 is over-expressed in diffuse large B-cell lymphoma ａnd peripheral T-cell lymphoma in opposite to normal lymphoid tissue. The tissue specificity of HDAC1 is ubiquitous, with higher levels in the heart, pancreas ａnd testis, ａnd lower levels in the kidney ａnd brain. |
| Description | HDAC1 Human Recombinant fused with 8 amino acid His tag at C-terminus produced in Hi-5 is a single, glycosylated, polypeptide chain containing 490 amino acids （1-482 a.a.） ａnd having a molecular mass of 56.2 kDa. The HDAC1 is purified by proprietary chromatographic techniques. |
| Source | Hi-5 Baculovirus. |
| Physical Appearance | Sterile Filtered colorless solution. |
| Formulation | The HDAC1 solution contains PBS （pH 7.4） ａnd 10% glycerol. |
| Stability | HDAC1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Purity | Greater than 90.0% as determined by（a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE. |
| Amino acid sequence | MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS AVKLNKTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEDD PDKRISICSS DKRIACEEEF SDSEEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKREVT EEEKTKEEKP EAKGVKEEVK LASRHHHHHH. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
HDAC1,Human,重组人组蛋白脱乙酰基酶1
