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PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
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PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
Synonyms Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. Introduction Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. Description PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Purity Greater than 90.0% as determined by SDS-PAGE. Amino Acid Sequence MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
PDE6D Human/ 磷酸二酯酶6D cGMP特异性Rod Delta
产品编号：ENZ-483
产品规格：5μg/20μg/1mg
产品规格：5μg/20μg/1mg
| Synonyms | Retinal rod rhodopsin-sensitive cGMP 3＇＇,5＇＇-cyclic phosphodiesterase subunit delta, Phosphodiesterase 6D cGMP-Specific Rod Delta, GMP-PDE delta, Protein p17, PDE6D, PDED. |
| Introduction | Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. PDE6D is an Oligomer composed of two catalytic chains （alpha ａnd beta）, an inhibitory chain （gamma） ａnd the delta chain. PDE6D interacts with RPGR, ARL2 ａnd ARL3. The catalytically active PDE6 is a heterodimer （αβ） that is controlled by two inhibitory γ subunits. Since PDE6D does not change the catalytic properties of PDEαβ, its function is still unanswered. PDE6D is expressed specifically in the retina. |
| Description | PDE6D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids （1-150 a.a.） ａnd having a molecular mass of 18.4kDa. PDE6D is fused to 8 amino acids His Tag at C-terminus ａnd purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile filtered colorless solution. |
| Formulation | The PDE6D protein solution contains 20mM Tris-HCl buffer （pH8.0）, 10% glycerol, 1mM DTT ａnd 100mM NaCl. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence | MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
PDE6D,Human,磷酸二酯酶6D,cGMP特异性Rod,Delta
