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HTLV-1 gp21/重组人T淋巴细胞病毒gp21

HTLV-1 gp21/重组人T淋巴细胞病毒gp21

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更新日期:2026/8/24 23:18:11

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简单介绍:HTLV-1 gp21/重组人T淋巴细胞病毒gp21

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相关标签:HTLV-1,gp21,重组人T淋巴细胞病毒gp21

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HTLV-1 gp21/重组人T淋巴细胞病毒gp21

产品编号:HIV-141
产品规格:100μg/500μg/1mg

Introdcution Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
Description The E.Coli derived recombinant protein contains the gp21 immunodominant region, 351-404 amino acids, the MW is 21kDa. Fused with a GST tag at N-Terminus.
Purification Method HTLV-1 gp21 was purified by proprietary chromatographic technique.
Purity HTLV-1 gp21 is >95% pure as determined by 10% SDS-PAGE (coomassie staining) and RP-HPLC.
Formulation 60mM NaCl, 50mM Tris-HCl, pH-8.0, 0.25% Sarkosil, 50% Glycerol, 10mM Glutathione.
Storage HTLV-1 gp21 protein is shipped at ambient temperature.
Upon arrival, Store at -20°C.
Stability Five years frozen. One month in solution at room temperature.
Application HTLV-1 gp21 can be used as an antigen in ELISA and Western Blots. Excellent reagent for correct detection of HTLV infections, with minimal specificity problems.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

HTLV-1,gp21,重组人T淋巴细胞病毒gp21

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