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Toll样受体6抗体 田源一抗
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价格:¥电议
更新日期:2026/9/8 4:40:34
生 产 地:其它
产品型号:Anti-TLR6/CD286
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详细内容
Toll样受体6抗体Anti-TLR6/CD286CD286; CD286 antigen; TLR 6; Toll like receptor 6 precursor.
360TIYO.COM-上海田源公司
性能参数:
中文名称:Toll样受体6抗体
英文名称:Anti-TLR6/CD286
别名:CD286; CD286 antigen; TLR 6; Toll like receptor 6 precursor.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The Toll like receptor family in mammal comprises a family of transmembrane proteins characterised by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. These proteins recognize different microbial products during infection and serve as an important phylogenetically conserved mediator/link between the innate and adaptive immune responses. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLRs characterised so far activate the MyD88/interleukin 1 receptor associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1 10) have been described.TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram positivebacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates proinflammatory cascades, but also can lead to apoptotic responses.Subcellular Location : Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein.Tissue Specificity : Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.Similarity : Belongs to the Toll-like receptor family.Contains 12 LRR (leucine-rich) repeats.Contains 1 LRRCT domain.Contains 1 TIR domain.Subunit : Binds TLR2 via their respective extracellular domains. Binds MYD88 via their respective TIR domains.Toll样受体6抗体的质量标准:
| ■其它名称: | CD286; CD286 antigen; TLR 6; Toll like receptor 6 precursor. |
| ■交叉反应: | hu, rat, mo, pig, hrs |
| ■产品类型: | 一抗 |
| ■应用领域: | /细胞生物/细胞膜受体 |
| ■蛋白分子: | predicted molecular weight: 84kDa |
| ■浓度值: | 1mg/1ml |
| ■物理性状: | Lyophilized or Liquid |
| ■免疫原: | KLH conjugated synthetic peptide derived from human TLR6 C-terminus |
| ■亚型: | polyclonal |
| ■纯化方法: | affinity purified by Protein A |
| ■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| ■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
| ■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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Toll样受体6抗体Anti-TLR6/CD286的相关产品目录:



1mg/1ml Toll样受体6抗体 Anti-TLR6/CD286 CD286; CD286 antigen; TLR 6; Toll like receptor 6 precursor.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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