Toll样受体9抗体 田源一抗

Toll样受体9抗体Anti-TLR9/CD289Toll-like receptor 9; CD 289; CD289; TLR 9; Toll like receptor 9; Toll like receptor 9 iso
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性能参数：

中文名称：Toll样受体9抗体
英文名称：Anti-TLR9/CD289
别名：Toll-like receptor 9; CD 289; CD289; TLR 9; Toll like receptor 9; Toll like receptor 9 iso
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：TLR9 is a member of the Toll like receptor （TLR） family which plays a fundamental role in pathogen recognition ａnd activation of innate immunity. TLRs are highly conserved from Drosophila to humans ａnd share structural ａnd functional similarities. They recognize pathogen associated molecular patterns （PAMPs） that are expressed on infectious agents, ａnd mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding this protein is predominantly expressed in lung, placenta, ａnd spleen, ａnd lies in close proximity to another family member, TLR8, on chromosome X.Subcellular Location : Endoplasmic reticulum membrane; Single-pass type I membrane protein （By similarity）. Endosome （By similarity）. Lysosome （By similarity）. Cytoplasmic vesicle, phagosome （By similarity）. Note=Relocalizes from endoplasmic reticulum to endosome ａnd lysosome upon stimulation with agonist （By similarity）.Tissue Specificity : Highly expressed in spleen, lymph node, tonsil ａnd peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes ａnd CD11c+ immature dendritic cells. Also detected in lung ａnd liver.Similarity : Belongs to the Toll-like receptor family. Contains 26 LRR （leucine-rich） repeats. Contains 1 TIR domain.Subunit : Interacts with MYD88 via their respective TIR domains （By similarity）. Interacts with CNPY3 （By similarity）. Interacts （via transmembrane domain） with UNC93B1 （By similarity）. Interacts with BTK.Toll样受体-9（Toll-like receptor 9,TLR9）是哺乳动物TLRs家族中一员,作为细胞表面的天然模式识别受体,主要参与免疫刺激序列（CpG序列）激活免疫细胞的信号传导,从而在天然抗感染免疫及联系天然免疫和获得性免疫中发挥重要作用。

Toll样受体9抗体的质量标准：

■其它名称：	Toll-like receptor 9; CD 289; CD289; TLR 9; Toll like receptor 9; Toll like receptor 9 iso
■交叉反应：	hu, mo, rat, cow, hrs, shp, pig, dog
■产品类型：	一抗
■应用领域:	/免疫学/神经生物学/信号转导/细胞周期蛋白
■蛋白分子：	predicted molecular weight: 111kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human TLR9
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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Toll样受体9抗体Anti-TLR9/CD289的相关产品目录：







1mg/1ml Toll样受体9抗体 Anti-TLR9/CD289 Toll-like receptor 9; CD 289; CD289; TLR 9; Toll like receptor 9; Toll like receptor 9 iso的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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