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Invivogen Poly(I:C) (HMW) tlrl-picb

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价格：￥电议

更新日期：2026/9/8 5:11:04

生产地：中国大陆

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简单介绍：Invivogen Poly(I:C) (HMW) tlrl-picb.北京优尼康现货供应

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相关标签：Invivogen,,Poly(I:C),(HMW),tlrl-picb

详细内容

TLR3 agonist - Polyinosine-polycytidylic acid High molecular weight

Polyinosinic-polycytidylic acid (usually abbreviated as poly(I:C) or poly(rI):poly(rC)) is a synthetic analog of double-stranded RNA (dsRNA), a molecular pattern associated with viral infection. Poly(I:C) activates the antiviral pattern recognition receptors TLR3, RIG-I/MDA5 ａnd PKR, thereby inducing signaling via multiple inflammatory pathways, including NF-kB ａnd IRF.

High Molecular Weight Poly(I:C) comprises long strands of inosine poly(I) homopolymer annealed to strands of cytidine poly(C) homopolymer. The average size of Poly(I:C) HMW is from 1.5 kb to 8 kb.

InvivoGen poly(I:C) HMW is a highly referenced as potent inducer of IFN both in vitro ａnd in vivo.

Poly(I:C) HMW is functionally validated for TLR3 potency using HEK-Blue™ TLR3 Cells. It is tested in TLR2 ａnd TLR4 cellular assays to confirm the absence of microbial contaminants (e.g. endotoxin or bacterial-membrane components).

Specifications

CAS number: 31852-29-6

Working concentration: 30 ng- 10 μg/ml

Endotoxin level:

Solubility: 5 mg/ml in physiological water (NaCl 0.9%) heated for 10 minutes at 65 - 70°C

Poly(I:C) is provided lyophilized ａnd is available in two quantities:

tlrl-pic: 10 mg
tlrl-pic-5: 50 mg

Sterile endotoxin-free physiological water (NaCl 0.9%), 10 ml is provided with catalog #tlrl-pic ａnd 2 x 25 ml with catalog #tlrl-pic-5

Poly(I:C) is shipped at room temperature

Upon receipt it should be stored at 4°C.

Upon resuspension, prepare aliquots of Poly(I:C) ａnd store at -20°C for long term storage. Store at 4°C for short term storage.

Lyophilized product is stable 1 year at 4°C when properly stored. Resuspended product is stable 1 month at 4°C ａnd 1 year at -20°C.

Avoid repeated freeze-thaw cycles.

Citations

TDS
MSDS
TDS
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Invivogen,,Poly(I:C),(HMW),tlrl-picb

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