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美天旎 CD3 Antibody, anti-human 130-093-387

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价格：￥电议

更新日期：2026/9/8 5:11:04

生产地：中国大陆

产品型号：130-093-387

简单介绍：Conjugate:pure-functional grade
Products used:130-093-387
Type of functional assay:in vitro activation and expansion of T cells together with CD2 and CD28 Antibodies

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详细内容

Specifications for CD3 Antibody, anti-human

Overview

The CD3 antibody recognizes the human CD3 antigen which is present on mature human T cells, thymocytes, ａnd NKT cells. The epie recognized by the antibody is located on the ε-chain of the CD3 complex. Clone OKT3 has been shown to activate T cell function.

Activation ａnd proliferation of T cells can be induced by interaction of the T cell receptor with peptide-MHC complexes expressed on the surface of antigen-presenting cells (APCs). The T cell receives a signal transduced through the CD3 complex. Cytokines or other costimulatory signals are required in addition. Activated T cells can be used for any downstream processes, such as cytokine analysis or immunoprecipitation. Cells can also be transfected with high efficiency.

Applications

The CD3 antibodies – functional grade are suited for functional assays, for example,

in vitro

activation ａnd expansion of T cells in combination with CD2 ａnd CD28 pure – functional grade antibodies, or CD2- ａnd CD28-Biotin – functional grade antibodies, ａnd Anti-Biotin MACSiBead™ Particles, cell culture grade.

Alternative names

CD3e, IMD18, T3E, TCRE

Detailed product information

Technical specifications

Clone	OKT3
Clonality	monoclonal
Isotype	mouse IgG2aκ
Host	mouse
Type of antibody	Primary antibodies, Functional-grade antibodies
Species	human
Antigen	CD3
Alternative names of antigen	CD3e, IMD18, T3E, TCRE
Molecular mass of antigen [kDa]	56(sum of molecular weights of subunits)
Distribution of antigen	NK cells, T cells, thymocytes
Entrez Gene ID	915, 916, 917
RRID	AB_1036144, AB_1036126