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Quidel Rat Bioactive PTH

点击次数：135

价格：￥电议

更新日期：2026/9/8 5:11:04

生产地：中国大陆

产品型号：60-2700

简单介绍：For Research Use Only. Not for use in diagnostic procedures

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For Research Use Only. Not for use in diagnostic procedures

Rat intact parathyroid hormone (PTH) is an 84 amino acid polypeptide produced by the parathyroid gland with its biological activity residing in the N-terminal region of the peptide. PTH plays an important role in maintaining the concentration of ionized calcium within the limits needed to achieve normal metabolic functions. When serum calcium levels are decreased the parathyroid gland increases secretion of the hormone which results in increased mobilization of calcium from skeletal reserves into the circulation. When levels of serum calcium are increased the secretion of PTH is reduced.

The similarities between rat ａnd human physiology relative to calcium metabolism make rat an excellent live-animal model for studying human skeletal disease ａnd in the pre-clinical evaluation of pharmacologic agents that may alter bone remodeling. Quantitation of only full-length biologically active rat intact PTH with this kit can provide a precise ａnd sensitive assessment of changes in bone ａnd mineral metabolism.

The Rat BioActive Intact PTH ELISA kit is a two-site enzyme-linked immunosorbent assay (ELISA) for the measurement of PTH in rat plasma or cell culture media. Two affinity purified goat polyclonal antibodies have been selected to detect only the full-length biologically active intact form of rat PTH. The antibody which recognizes epies within the C-terminal portion of the peptide is biotinylated for capture. The other antibody which recognizes the initial
N-terminal epie is conjugated with the enzyme horseradish peroxidase (HRP) for detection.

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