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FGF-7
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价格：￥电议
更新日期：2026/8/7 18:57:43
生 产 地：中国大陆
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详细内容
Keratinocyte Growth Factor-1 (KGF-1/FGF⁻⁷) is one of 23 known members of the FGF family. All FGFs have two conserved cysteine residues ａnd share 30 - 50% sequence identity at the amino acid level. Proteins of this family play a central role during prenatal development ａnd postnatal growth ａnd regeneration of variety of tissues, by promoting cellular proliferation ａnd differentiation. KGF-1/FGF⁻⁷ is a mitogen factor specific for epithelial cells ａnd keratinocytes ａnd signals through FGFR 2b. KGF-1/FGF⁻⁷ plays a role in kidney ａnd lung development, angiogenesis, ａnd wound healing.
▍Source
Recombinant Human FGF⁻⁷/KGF-1 is expressed from Escherichia coli. It contains AA Cys32-Thr194. Predicted molecular mass 21.7 kDa. This protein carries a polyhistidine tag at the N-terminus.
▍Endotoxin
Less than 1.0 EU per μg by the LAL method.
▍AA Sequence
CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT
▍Purity
Purity >95% as determined by SDS-PAGE.
▍Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
▍Reconstitution
Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots ａnd stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.
▍Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to ⁻⁷0°C for 12 months in lyophilized state;
⁻⁷0°C for 3 months under sterile conditions after reconstitution.
▍SDS-PAGE
Human FGF⁻⁷, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
