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光遗传系统
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更新日期:2021/6/16 13:43:33
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详细内容
采用光遗传进行点燃癫痫研究


Cortical EEG and hippocampal depth electrode activity with prefrontal cortex glutamate changes during kindling stimulation with blue (445 nm) light in a transgenic mouse from Jackson Laboratory expressing channelrhodopsin.
Application of 40 Hz stim frequency (10% duty cycle, 600 mA) 10 seconds ON, 10 seconds OFF periods for one hour intervals (blue bars) results in increased power in the Gamma frequency (25-50 Hz) range and decreased NREM sleep by an average of 42 percent during time when stim was applied.
软件





Cortical EEG and hippocampal depth electrode activity with prefrontal cortex glutamate changes during kindling stimulation with blue (445 nm) light in a transgenic mouse from Jackson Laboratory expressing channelrhodopsin.
Light pulses (20 Hz, 10% duty cycle, 600 mA) were delivered for 20 seconds. The blue LED power measured prior to implant was 130 mW/mm2 .
光遗传改变睡眠状态


光遗传改变睡眠状态



Application of 40 Hz stim frequency (10% duty cycle, 600 mA) 10 seconds ON, 10 seconds OFF periods for one hour intervals (blue bars) results in increased power in the Gamma frequency (25-50 Hz) range and decreased NREM sleep by an average of 42 percent during time when stim was applied.
软件



癫痫分析软件 动物活动视频跟踪分析, 活动实时跟踪记录
自动癫痫发作识别、热密度图谱、光谱图、时间分析、功效分析
癫痫统计: 平均持续时间、 癫痫发作间隔时间、峰值频率等


睡眠分析软件
三种睡眠评分手段: 手动、簇、阈值评分
实时睡眠图(hypnograms)、波谱图、热点图辅助评判睡眠状态。功效分析、峰值频率分析
我公司也可以提供相关实验服务,详情来电联系


