PE标记CEA抗体说明书

Cat. Number:RY-K4792M-PE

Quantity size: 100ul

Concentration:1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 ａnd 50% Glycerol.

Background:CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) ａnd 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily ａnd are composed of one Ig variable-like (IgV) ａnd a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte ａnd dendritic cell activation, receptors of Neisseria species ａnd other bacteria.

Also known as:Carcino Embryonic Antigen CEA; CEACAM 5; CEACAM-5; Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; CD66e; CD66e antigen; CEA; CEACAM5; DKFZp781M2392; Meconium antigen 100.

Specificity:Mouse Monoclonal(Clone number:4F3) IgG, affinity

           purified by Protein A.

           Reacts with: Human, .         

           Immunogen: KLH conjugated synthetic peptide

           derived from Human CEA/CD66e/CEACAM5.

           Predicted Molecular Weight: 150-200kDa.

Storage:Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:ICC=1:50-200  IF=1:50-200   

            Excitation spectrum: 496nm ,564nm 
            Emission spectrum: 578nm 

            Not yet tested in other applications. 

            Optimal working dilutions must be determined by the end user.