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Recombinant Human IL-1α Peprotech厂家直销
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更新日期：2026/8/7 19:27:25
生 产 地：中国大陆
产品型号：200-01A
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相关标签：Recombinant,Human,IL-1α,Peprotech厂家直销
详细内容
Recombinant Human IL-1α Peprotech厂家直销
产品编号:
200-01A
别名:
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
描述:
IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, ａnd other epithelial cells. Both IL-1α ａnd IL-1β bind to the same receptor ａnd have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity ａnd the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
氨基酸序列:
SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 109units/mg.
交叉反应:
Cow, Monkey, Mouse, Human, Frog, Pig
研究领域:
 | 血管生成/ 心血管 |  | 癌症 |
 | 糖尿病/ 体重调节 |  | 免疫系统 |
 | 炎症 |  | 神经生物学 |
 | 增殖 |  | 干细胞及分化 |
 | 创伤修复 |  | 过敏 |
 | 移植 | ||
原产国:
USA
仅用于研究。不适用于诊断或治疗。
Recombinant,Human,IL-1α,Peprotech厂家直销
