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磷酸化G蛋白信号转导调节因子19抗体;phospho-RGS19 (Ser24)
点击次数:89
价格:¥电议
更新日期:2026/8/25 1:14:10
生 产 地:中国大陆
产品型号:50ul;100ul
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相关标签:磷酸化G蛋白信号转导调节因子19抗体;phospho-RGS19,(Ser24);抗体
详细内容
基本信息
产品名称:磷酸化G蛋白信号转导调节因子19抗体;phospho-RGS19 (Ser24)
规格: 50ul;100ul
介绍;
产品名称:磷酸化G蛋白信号转导调节因子19抗体;phospho-RGS19 (Ser24)
规格: 50ul;100ul
介绍;
别 名RGS19(phospho S24); RGS19(phospho Ser24); G alpha interacting protein; GAIP; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G protein signalling 19; RGSGAIP; RGS19_HUMAN; Regulator of G-protein signaling 19; RGS19; G-alpha-interacting protein.
产品类型磷酸化抗体
研究域肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应(predicted: Human, Mouse, Rat, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量25kDa
细胞定位细胞膜
磷酸化G蛋白信号转导调节因子19抗体;phospho-RGS19 (Ser24)性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated Synthesised phosphopeptide derived from human RGS19 around the phosphorylation site of Ser24:M(p-S)SH
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
磷酸化G蛋白信号转导调节因子19抗体;phospho-RGS19 (Ser24)产品介绍G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase activating protein that functions to down regulate Galpha i/Galpha q linked signaling.
Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Subunit:
Interacts with GIPC PDZ domain.
Subcellular Location:
Membrane; Lipid-anchor.
Tissue Specificity:
Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
Post-translational modifications:
Fatty acylated. Heavily palmitoylated in the cysteine string motif.
Phosphorylated, mainly on serine residues.
Similarity:
Contains 1 RGS domain.
SWISS:
P49795
Gene ID:
10287
磷酸化G蛋白信号转导调节因子19抗体;phospho-RGS19,(Ser24);抗体



