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大鼠胰腺外分泌细胞
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更新日期：2026/8/7 18:14:45
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详细内容
| 细胞名称 | AR42J暂不供应大鼠胰腺外分泌细胞 |
| 描述 | 在肾上腺皮质激素刺激下可诱导出外分泌活性，并伴有广泛的内质网重构。 |
| 动物种别 | 大鼠 |
| 性别 | *** |
| 组织来源 | 胰腺外分泌细胞肿瘤 |
| 形态 | 上皮细胞 |
| 培养基和添加剂 | F12K培养基(SIGMA,货号N3520，添加NaHCO3 2.5g/L)，80%；优质胎牛血清，20%。 气相：空气，95%；二氧化碳，5%。 温度：37摄氏度。 |
| 供应限制 | A。仅供研究之用。 |
| REFERENCE | Jessop NW , Hay RJ . Characteristics of two rat pancreatic exocrine cell lines derived ATCC: Cell Biology Collection: Cell Biology Catalog http://www.atcc.org/common/catalog/numSearch/numResults.cfm 第2页 共2页2005-8-3 9:47 from transplantable tumors. In Vitro 16: 212, 1980. 22384: Longnecker DS , et al. Transplantation of azaserine-induced carcinomas of pancreas in rats. Cancer Lett. 7: 197-202, 1979. PubMed: 509403 22884: Cockell M , et al. Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas. Mol. Cell. Biol. 9: 2464-2476, 1989. PubMed: 2788241 22978: Roux E , et al. The cell-specific transcription factor PTF1 contains two different subunits that interact with the DNA. Genes Dev. 3: 1613-1624, 1989. PubMed: 2612907 23083: Seva C , et al. Lorglumide ａnd loxiglumide inhibit gastrin-stimulated DNA synthesis in a rat tumoral acinar pancreatic cell line (AR42J). Cancer Res. 50: 5829-5833, 1990. PubMed: 2393852 23152: Rajasekaran AK , et al. Structural reorganization of the rough endoplasmic reticulum without size expansion accounts for dexamethasone-induced secretory activity in AR42J cells. J. Cell Sci. 105: 333-345, 1993. PubMed: 7691838 23222: Longnecker DS , et al. Effect of age on nodule induction by azaserine ａnd DNA synthesis in rat pancreas. J. Natl. Cancer Inst. 58: 1769-1775, 1977. PubMed: 864754 23408: Huang Y , Hui DY . Cholesterol esterase biosynthesis in rat pancreatic AR42J cells. Post- transcriptional activation by gastric hormones. J. Biol. Chem. 266: 6720-6725, 1991. PubMed: 2016288 23412: Menniti FS , et al. Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells. J. Biol. Chem. 268: 3850-3856, 1993. PubMed: 8382679 23421: Logsdon CD , et al. Glucocorticoids increase amylase mRNA levels, secretory organelles, ａnd secretion in pancreatic acinar AR42J cells. J. Cell Biol. 100: 1200-1208, 1985. PubMed: 2579957 23552: Zhao H , et al. Regulation of intracellular Ca2+ oscillation in AR42J cells. J. Biol. Chem. 265: 20856-20862, 1990. PubMed: 1701171 23554: Zhao H , Muallem S . Inhibition of inositol 1,4,5-trisphosphate-mediated Ca2+ release by Ca2+ in cells from peripheral tissues. J. Biol. Chem. 265: 21419-21422, 1990. PubMed: 2174872 23556: Ihara H , Nakanishi S . Selective inhibition of expression of the substance P receptor mRNA in pancreatic acinar AR42J cells by glucocorticoids. J. Biol. Chem. 265: 22441-22445, 1990. PubMed: 1702421 48308: Adell T , et al. Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells. Cell Growth Differ. 11: 137-147, 2000. PubMed: 10768861 48309: Seva C , et al. Growth-promoting effects of glycine-extended progastrin. Science 265: 410-412, 1994. PubMed: 8023165 48311: Negre F , et al. Autocrine stimulation of AR4-2J rat pancreatic tumor cell growth by glycine-extended gastrin. Int. J. Cancer 66: 653-658, 1996. PubMed: 8647628 48312: Bertrand V , et al. Inhibition of gastrin-induced proliferation of AR4-2J cells by calcium channel antagonists. Int. J. Cancer 56: 427-432, 1994. PubMed: 7508895 57433: Mashima H , et al. Betacellulin ａnd activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells. J. Clin. Invest. 97: 1647-1654, 1996. PubMed: 8601630 57434: Palgi J , et al. Transcription factor expression ａnd hormone production in pancreatic AR42J cells. Mol. Cell. Endocrinol. 165: 41-49, 2000. PubMed: 10940482 90275: Mashima H , et al. Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor. Endocrinology 137: 3969-3976, 1993. PubMed: 8756573 90276: Silver K , Yao F . ARIP cells as a model for pancreatic beta cell growth ａnd development. Pancreas 22: 141-147, 2001. PubMed: 11249068 |
| 中文名称 | 大鼠胰腺外分泌细胞 |
