文章关键词:N3 C2 NHS ester,3-Azidopropanoic acid NHS ester,Azide C2 NHS,3-叠氮丙酸N-琥珀酰亚胺酯,叠氮-C2-琥珀酰亚胺酯,3-叠氮丙酸N-活性酯,叠氮-C2-活性酯,850180-76-6
一、基本信息
【性质简介】:The N3-C2-NHS ester, as a unique and non degradable ADC linker, plays a crucial role in the synthesis of antibody conjugated drugs. The design of this linker cleverly combines N3 and C2 groups, and through the introduction of NHS ester functional groups, it can efficiently and stably connect with antibodies. During the synthesis process, N3-C2-NHS ester can be covalently linked to antibody molecules to form stable coupling products. This coupling product can be specifically recognized and bound to target cells in vivo, and then enter the cell interior through an internalization process, releasing small molecules. N3-C2-NHS ester, as an non degradable ADC linker, plays a crucial role in the synthesis of antibody conjugated drugs.
【中文名】:3-叠氮丙酸N-琥珀酰亚胺酯,叠氮-C2-琥珀酰亚胺酯,3-叠氮丙酸N-活性酯,叠氮-C2-活性酯
【英文名】:N3 C2 NHS ester,3-Azidopropanoic acid NHS ester,Azide C2 NHS
【CAS号】:850180-76-6
【化学式】:C7H8N4O4
【分子量】:212.17
【结构式】:
二、详情介绍
【外观】:固体/粉末
【溶解性】:溶于大部分有机溶剂
【规格】:10mg、25mg、1g(接受各种规格的定制服务,具体可以线上咨询)
【纯度】:95%+
【储存条件】:本品应密封避光,储存于阴凉、干燥、通风处,避免反复冻融,储液应该立即使用
【注意事项】:陕西新研博美生物科技有限公司提示,试剂仅用于科学研究或者工业应用等非医疗目的,非药用,非食用!
三、相关试剂
Bis-PEG1-NHS ester
Bis-PEG2-NHS ester
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Bis-PEG7-NHS ester
Bis-PEG6-NHS ester
Bis-PEG4-NHS ester
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Bis-PE21 NHS ester
Bis-PEG9-NHS ester
Acid-PEG3-NHS ester
Bis-PEG25-NHS ester
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Acid-PEG5-NHS ester
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关键词:N3 C2 NHS ester 3-Azidopropanoic acid NHS ester Azide C2 NHS 3-叠氮丙酸N-琥珀酰亚胺酯 叠氮-C2-琥珀酰亚胺酯 3-叠氮丙酸N-活性酯 叠氮-C2-活性酯 850180-76-6