Rabbit Anti-TIMP-1

Rabbit Anti-TIMP-1

Catalog Number : RS-0415R

Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases （MMPs）, a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, ａnd may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines ａnd hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene ａnd is transcribed in the opposite direction. [provided by RefSeq].

Specificity : · anti-TIMP-1 is a rabbit monoclonal antibody unconjugated

· specific for TIMP-1 of hu, rat, mo

· epitope mapping in the C-terminalse of TIMP-1 of hu, rat, mo

· use for western blotting, elisa, immunoprecipitation ａnd immunohistochemistry

· Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt: 34kDa

Application: ·Western blotting 1:100-500

·Immunohistochemistry 1:100-500

·ELISA 1:500-1000

·Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.